Under The Microscope

This is a blog dedicated to sharing and compiling many different images from under the microscope. From living to non-living, we can appreciate the invention of the microscope that has allowed us to see the into world of the very small.
Blood-brain barrier breakdown. Confocal light micrograph of a section through the brain showing a breakdown in the blood-brain barrier. A fluorescent tracer (orange) has been injected into the blood vessels (round, black) and is leaking out of them into the surrounding brain tissue. The barrier, which consists of tightly packed endothelial cells, protects the brain from potentially harmful molecules and micro-organisms. If it is breached, by injury or disease, it can lead to the death of the surrounding tissue. Within the brain tissue, neurons (nerve cells, blue) and glial cells (support cell, green) are seen. Glial cells provide structural support, nutrients and oxygen for neurons, and are also thought to help maintain the blood-brain barrier.
+ December 12th, 2011
Blood-brain barrier. Confocal light micrograph of a section through a blood vessel in the brain, showing the arrangement of cells that form the blood-brain barrier. The lumen (interior) of the vessel runs horizontally across the upper frame. The endothelial cells that line the blood vessels of the brain are packed more tightly than elsewhere in the body. This barrier protects the brain from many potentially harmful molecules and micro-organisms, but also presents a challenge for the administration of drugs to the brain. Surrounding the blood vessel are glial cells (green), which provide structural support for neurons (nerve cells, red) and supply them with nutrients and oxygen. It is also thought that glial cells help maintain the blood-brain barrier.
+ December 12th, 2011
Microglia, Mouse, Cortex x20 (ICC stain)
+ December 11th, 2011
Forebrain, Rat (GOLGI stain)
+ September 18th, 2011
Microglia, mouse, cerebellum x20 (ICC stain)
+ July 9th, 2011
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